The Bruggeman lab

New paper in Nucleid Acid Research on mammalian gene expression!

See link to paper. Here we describe a method to infer a transcription model from the dynamics of multiple qPCR-primers along the length of a gene. We show that this model successfully predicts the identity of an inhibited molecular process, splicing in our case, from a second set of experimental data, by refitting the basal model on a parameter-by-parameter basis.